Newborn Solutions
Supplement Evidence Guide
What research says about supplements, by health condition — evidence grades, plain-language summaries, and the cautions first. Compiled October 2026.
Not medical advice. Supplements don’t cure or replace treatment for any disease. Many interact with medicines, kidney or liver conditions, pregnancy and surgery. Check with your doctor or pharmacist first.
Affiliate links you can buy and trust — nurse-checked picks. We may earn a small commission at no extra cost to you.
Before taking any supplement
- Tell your clinician everything you take, including herbs. Blood thinners, antidepressants, transplant and cancer drugs have the most serious interactions.
- Pause and ask about supplements before surgery or procedures.
- Prefer products with third-party testing (USP, NSF, ConsumerLab). Label contents are not verified by FDA before sale.
- Get lab-confirmed deficiencies treated at doses your clinician sets. More is not better.
- Report bad reactions to FDA at safetyreporting.hhs.gov.
Keep it current: open sources to build on
- NIH Dietary Supplement Label Database (DSLD): free, public, maintained by NIH’s Office of Dietary Supplements, with a bulk API download guide. It links to ODS fact sheets and PubMed searches. dsld.od.nih.gov
- NIH ODS fact sheets: the primary evidence summaries for each nutrient and ingredient. ods.od.nih.gov
- SUPP.AI + GitHub allenai/sdi-detection: evidence sentences for supplement–drug interactions pulled from literature, with search API and datasets. supp.ai
- SuppKG and iDISK: research knowledge graphs of supplement information built from PubMed and trusted sources. Search arXiv for “SuppKG” and “iDISK”.
- MedlinePlus and NCCIH: plain-language herb and supplement pages from the U.S. government.
- Hugging Face: only general nutrition and food datasets turned up. No ready-made supplement-by-condition dataset was found, so treat any model output as unverified.